Developing Next Generation Genomic CDS
Traditionally, genomic-based clinical decision support (CDS) rules have been implemented as pop-up alerts that interrupt the clinical workflow. In addition, the CDS rules usually consider only a single gene at a time. As clinical-grade whole exome and whole-genome sequencing becomes more common, technologies are needed to interpret patient genomic data and deliver comprehensive, integrated knowledge to a clinician at the right time. In partnership with the Center for Individualized Medicine and the Office of Information and Knowledge Management, we are developing novel systems that provide scalable next-generation genomic CDS. In collaboration with the Medication Safety Code initiative, we are exploring technologies that will enable patients to access personalized pharmacogenomics recommendations using mobile devices.