The gastrointestinal physiology laboratory of Gianrico Farrugia, M.D., located in the Guggenheim Building on Mayo Clinic's campus in Rochester, Minn., aims to further understand the regulation of gastrointestinal motility in both health and disease.

Dr. Farrugia's laboratory works in close collaboration and shares similar goals with the laboratories of Joseph H. Szurszewski, Ph.D., Tamas Ordog, M.D., David R. Linden, Ph.D., and Michael G. Sarr, M.D. These laboratories collaborate on most projects and have a common interest in gastrointestinal smooth muscle cells, interstitial cells of Cajal and enteric nerves.

Dr. Farrugia's laboratory is also an integral part of the Center for Cell Signaling in Gastroenterology, and a close collaborative effort exists with the research and clinical programs of other members of the Enteric Neuroscience Program, including investigators in the Clinical Enteric Neuroscience Translational and Epidemiological Research Program. Research on animal models of diabetic gastroparesis in the laboratory is supported by a program project grant — Pathobiology of the Enteric System — led by Dr. Szurszewski as principal investigator.