Selected Publications

  • Knowlton, R., Johnston, R., Whitby, F., Realini, C., Zhang, Z., Rechsteiner, M., Hill, C.P. Structure of the Proteasome Activator REGα. Nature. 1997; 390: 639-643.
  • Zhang, Z., Clawson, A., Realini, C., Jensen, C., Knowlton, J.R., Hill, C.P., Rechsteiner, M.  Identification of an Activation Region in the Proteasome Activator REGα. Proc. Natl. Acad. Sci. USA. 1998; 95: 2807-2811.
  • Zhang, Z. Shibahara, K., Stillman, B. PCNA Connects DNA Replication Epigenetic Inheritance in Yeast. Nature. 2000; 408, 221-225.
  • Huang, S.B., Zhou, H., Katzmann, D., Hochstrasser, D., Atanasova, E., Zhang, Z. Rtt106p is a Histone Chaperone Involved in Heterochromatin Mediated Silencing. Proc. Natl. Acad. Sci. USA. 2005; 102: 13410-13415.
  • Han, J., Zhou, H., Horazdovsky, B., Zhang, K., Xu, R. M., Zhang, Z. Rtt109 Acetylates Histone H3 Lysine 56 and Functions in DNA Replication. Science. 2007; 315: 653-655.
  • Huang, S., Zhou, H., Tarara, J., Zhang, Z. A Novel Role of Histone Chaperones CAF-1 and Rtt106 in Heterochromatin Silencing. EMBO J. 2007; 26: 2274-2283.
  • Collins, S.R., Miller, K.M., Maas, N.L., Roguev, A., Chu, C.S., Schuldiner, M., Gebbia, M., Cheng, B., Han, J., Recht, J., Fillingham, J., Ingvarsdottir, K., Shales, M., Erkmann, J.A., Ding, H., Xu, H., Andrews, B., Ingles, C., Boone, C., Emili, A., Kaufman, P.D., Allis, C.D., Berger, S.L., Brown, G.W., Hieter, P., Zhang, Z., Toczyski, D. P., Weissman, J.S., Greenblatt J. F., Krogan N.F. Genetic Interactions Reveal the Functional Relationships Within and Between Protein Complexes Involved in Chromsome Biology. Nature. 2007; 446: 806-810.
  • Li1*, Q., Zhou1*, H., Wurtele2, H., Davies1, B., Horazdovsky1, B., Verreault2, A., Zhang1, Z. Acetylation of histone H3 lysine 56 regulates CAF-1 dependent nucleosome assembly. Cell. 2008; 134: 244-255.
  • Burgess RJ, Zhou H, Han J, and Zhang, Z. A role for Gcn5 in replication-coupled nucleosome assembly. Molecular Cell. 2010; 37: 49-480.
  • Han J, Li Q, McCullough L, Kettlekamp C, Formosa T, and Zhang, Z. Ubiquitylation of FACT by the cullin-E3 ligase Rtt101 connects FACT to DNA replication. Genes & Development. 2010; 24: 1385-1490.

Other Publications

  • Realini, C., Jensen, C., Zhang, Z., Johnston, S., Knowlton, J.R., Hill, C.P., Rechsteiner, M. Characterization of Recombinant REGα, REGβ, and REGγ. Proteasome Activators. J. Biol. Chem. 1997; 272: 25483-25492.
  • Zhang, Z., Realini, C., Clawson, A., Endicott, S., Rechsteiner, M. Proteasome Activation by REG Molecules Lacking Homolog-Specific Inserts. J. Biol. Chem. 1998; 273: 9501-9509.
  • Zhang, Z., Clawson, A., Rechsteiner, M. The Proteasome Activator 11S REG or PA28: Contribution by Both α and β Subunits to Proteasome Activation. J. Biol. Chem. 1998; 273: 30660-30668.
  • Zhang, Z., Krutchinsky, A., Endicott, S., Realini, C. Standing K.G., Rechsteiner M. The Proteasome Activator 11S REG or PA28: Recombinant REGα/REGΒ Hetero-oligomers are Heptamers. Biochemistry. 1999; 38: 5651-5658.
  • *Zhang, Z., *Hayashi, M.K., *Merkel, O., Stillman, B., Xu, R.M. Structure and Function of the N-terminal BAH Domain of ORC1 in Transcriptional Silencing. EMBO J. 2002; 21: 4600-4611 (*equal contribution)
  • Zhou, H., Madden, B., Muddiman, D., Zhang Z. Chromatin Assembly Factor 1 Interacts with Histone H3 Methylated at Lysine 79 in the Processes of Epigenetic Silencing and DNA Repair. Biochemistry. 2006; 45: 2852-2861.
  • Han, J., Zhou, H., Li, Z., Xu, R. M., Zhang, Z. The Rtt109-Vps75 Histone Acetyltransferase Complex Acetylates Non-nucleosomal Histone H3. J. Biol. Chem. 2007; 282: 14158-14164.
  • Han, J., Zhou, H. Li, Z., Xu, R. M., Zhang, Z. Acetylation of H3 Lysine 56 Catalyzed by Rtt109 and Regulated by Asf1 Is Required for Replisome Integrity. J. Biol. Chem. 2007; 282: 28587-28596.
  • Burgess, R., Jenkins, R., Zhang, Z. Epigenetic Changes in Gliomas. Cancer Biol. Ther. 2008; 7: 2642.
  • Yuan, J, Pu, M, Zhang, Z, Lou, Z. Histone H3-K56 acetylation is important for genome stability in mammals. Cell Cycle. 2009; 8: 1747-1753.
  • Burgess, RJ. Guy, MP, Zhang, Z. Fueling transcriptional silencing with Gas1. Proc Natl Acad Sci. 2009; 106: 10879-10880.
  • Li Q, Fazly AM, Zhou H, Huang S, Zhang Z, and Stillman B. The elongator complex interacts with PCNA and modulates transcriptional silencing and sensitivity to DNA damaging agents. PLoS Genetics. 2009; 5.
  • Burgess, RJ and Zhang, Z. Histones, histone chaperones and nucleosome assembly. Protein & Cell. 2010; 1: 607-612.
  • Burgess, RJ and Zhang, Z. Roles for Gcn5 in promoting nucleosome assembly and maintaining genome integrity. Cell Cycle. 2010; 9: 2979-2985.