Basic and translational research in the Biomechanics Laboratory at Mayo Clinic includes a wide range of studies that examine joint and soft tissue mechanics, characterize tissue properties, and assess devices and surgical procedure outcomes. Studies make use of both standard and custom-made testing equipment.

Two particular areas of focus in the laboratory are:

  • Developing novel protocols for biomechanical research using medical imaging technology, such as fluoroscopy, ultrasound, CT and MRI
  • Investigating the influence of mechanical stimulus on cell function and organization in tissue (mechanobiology), which will facilitate the future success of tissue engineering

Kai-Nan An, Ph.D., of Mayo Clinic in Rochester, Minn., directs the Biomechanics Laboratory. The laboratory was founded in 1971 by Edmund Y. Chao, Ph.D., a Mayo Clinic researcher who was interested in the development and implementation of total joint replacements as a result of the Food and Drug Administration approving the first total hip joint replacement in 1970.