Chronic Liver Disease Studies
Comparative Effectiveness of Advanced Diagnostic Imaging for Hepatic Fibrosis
Jayant A. Talwalkar, M.D.
Secretary phone: 507-284-4823
- To prospectively identify and compare the diagnostic accuracies of quantitative elasticity imaging with serum marker panels for detecting hepatic fibrosis measured by liver biopsy in human subjects
- To prospectively determine the clinical effectiveness of quantitative elasticity imaging techniques with serum marker panels for detecting hepatic fibrosis in human subjects
Prospective comparative effectiveness study of serum fibrosis markers, ultrasound-based transient elastography, and magnetic resonance elastography (MRE) versus liver biopsy for the detection of hepatic fibrosis inpatients with nonalcoholic fatty liver disease and chronic hepatitis C. In addition to diagnostic accuracy, several parameters assessing clinical effectiveness, including resource utilization and patient preferences for all testing modalities, will be measured.