Location

Rochester, Minnesota

Contact

Yaszemski.Michael@mayo.edu

Summary

Our Tissue Engineering and Polymeric Biomaterials Laboratory investigates bone, cartilage, and spinal cord regeneration using synthetic polymeric scaffolds, cells, and controlled delivery of bioactive molecules. We are equipped to perform polymer synthesis and characterization, and scaffold fabrication utilizing injectable techniques and solid free form fabrication techniques. We culture cell-polymer constructs, study delivery kinetics of bioactive molecules from microparticles and microparticle-scaffold combinations, and study these scaffold-cell-biomolecule combinations in vivo. We investigate musculoskeletal sarcoma biology and work on the controlled local delivery of chemotherapeutic agents to osteosarcoma. We have a fully equipped molecular biology and bone histomorphometry laboratory. Our focus is on translational research for current clinical needs.

Recent Publications

See my publications

Professional Details

Primary Appointment

  1. Orthopedic Surgery

Joint Appointment

  1. Physiology and Biomedical Engineering

Academic Rank

  1. Professor of Biomedical Engineering
  2. Professor of Orthopedics

Education

  1. Senior Research Fellowship Center for Biotechnology Engineering, Northeastern University
  2. PhD - Major: Chemical Engineering
    Thesis: ""A Temporary Replacement for Trabecular Bone: The Design, Synthesis, and Evaluation of a Novel Degradable Polymeric Biomaterial.""
    Massachusetts Institute of Technology
  3. Research Fellowship - Orthopaedic Biomechanics Orthopaedic Biomechanics Laboratory and Department of Orthopaedic Surgery, Beth Israel Hospital, Harvard Medical School
  4. Clinical Fellowship - Spine Surgery Orthopaedic Biomechanics Laboratory and Department of Orthopaedic Surgery, Beth Israel Hospital, Harvard Medical School
  5. Resident - Orthopaedic Surgery Wilford Hall Medical Center, United States Air Force
  6. Internship - General Surgery Wilford Hall Medical Center, United States Air Force
  7. MD Georgetown University School of Medicine
  8. MS - Major: Chemical Engineering
    Thesis: ""The Preparation And Characterization Of A Vinyl Acetate- Diallylamine Copolymer Latex To Be Used As An Immunological Reagent""
    Lehigh University
  9. BS - Major: Chemical Engineering Lehigh University
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BIO-00027371

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