Location

Rochester, Minn

Contact

Schrum.Adam@mayo.edu

SUMMARY

The laboratory is interested in how the immune system decides whether to destroy or tolerate tissues bearing persistent antigens. We first focus on the T cell antigen receptor, and how its structure, multi-subunit composition, and biochemical functions operate throughout the course of immune responses. We then study how the many other proteins and pathways involved in T cell signaling cooperate to compose a network with emergent properties to determine immune fate. Using cellular, molecular, biochemical, and proteomic techniques, we examine these processes in T cell responses to tumors and transplanted tissues.

PUBLICATIONS

See my publications

PROFESSIONAL DETAILS

Academic Rank

  1. Assistant Professor of Immunology

EDUCATION

  1. Postdoctoral Fellowship University of Basel, University-Hospital
  2. Ph.D. - Immunology University of Pennsylvania School of Medicine
  3. MS - Molecular Biology Brigham Young University
  4. BS - Molecular Biology Brigham Young University

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BIO-00095885

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