Rochester, Minnesota




The health care sector has several quality problems related to safety, efficiency, outcomes and timeliness. Traditionally, these problems in complex systems have been studied in isolation within human factors and operations research, with restricted impact on care delivery. The research of Kalyan S. Pasupathy, Ph.D., focuses on a unified framework of systems engineering through data-driven modeling to better understand such systems and redesign processes. The knowledge gained from Dr. Pasupathy's research ensures that one dimension of quality does not compromise another and that this knowledge is translated into decision support systems to impact care delivery.

Focus areas

  • Establishing the emergency department clinical engineering learning laboratory, which studies teamwork and process flow
  • Discovering patterns of cardiotoxicity in breast cancer patients undergoing chemotherapy and developing decision support systems to proactively predict dysfunction and involve cardiologists
  • Studying the boarding of mental and behavioral health patients in the emergency department due to lack of inpatient beds
  • Studying surgeries (spine, colorectal and urology) to improve utilization through better prediction and new heuristics and decision support systems for scheduling using surgeon preferences
  • Reducing sentinel events by studying human factors patterns and reducing surgeon fatigue
  • Research and teaching simulation, using Simio Academic Software, under a grant from Simio LLC

Significance to patient care

Developing a better understanding of systems and decision support improves care delivery in a number of areas. This includes reduced wait times and length of stay, improved communication, increased patient satisfaction in the emergency department, timely diagnosis and treatment of cardiotoxicity, timely delivery of care to mental and behavioral health patients, reduced surgery delays, avoided sentinel events, and reduced surgeon burnout.

Professional highlights

  • Team won INFORMS Innovative Applications in Analytics Award, 2015
  • Standing member on Agency for Healthcare Research and Quality study section, 2015-2018
  • New Faces of Engineering award by DiscoverE (formerly the National Engineers Week Foundation) based on innovation, contributions to engineering and significant impact on public welfare, 2009
  • Service to Patient-Centered Outcomes Research Institute and National Science Foundation panels, 2008-present
  • Goodeve Medal award to the research team at The Royal Society in London for the most outstanding contribution to the philosophy, theory and practice of operations research, 2008


See my publications


Academic Rank

  1. Associate Professor of Healthcare Systems Eng


  1. PhD - Concentration: Management Systems Virginia Polytechnic Institute & State University
  2. MS - Concentration: Operations Research Virginia Polytechnic Institute & State University
  3. BE - Concentration: Operations Management Bharathiar University

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