Location

Rochester, Minnesota

Contact

Ogut.Ozgur@mayo.edu

Summary

Muscle contraction is defined by the cyclical interaction between actin and myosin, an association primarily governed by the troponin complex in cardiac muscles. During pathophysiological conditions, efficient regulation of muscle contraction may be compromised by changes in the post-translational state and function of the contractile proteins or by alterations in the upstream signaling pathways that serve to modulate myocardial contractility.

My research examines the biophysical mechanism of cardiac muscle contraction under normal and pathophysiological states, as well as defining altered second messenger signaling pathways that modulate the protein-protein interactions governing the allosteric mechanism of regulation in cardiac muscles.

Recent Publications

See my publications

Professional Details

Education

  1. Post-doctoral Fellowship - Laboratory of Dr. Frank Brozovich Case Western Reserve University
  2. PhD - Cell Biology Case Western Reserve University
  3. MSc - Biochemistry and Molecular Biology University of Calgary
  4. BSc - Biochemistry University of Calgary
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BIO-00094558

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