Summary
High resolution nuclear magnetic resonance (NMR) spectroscopy of biological systems.
Specific areas of study include:
Multi-dimensional NMR of biomolecules
- determination of 3D structure of polypeptides and small proteins in solution
- techniques for separation of structural and dynamical parameters and structure refinement
- NMR study of internal mobility of proteins
In vivo NMR spectroscopy
- 1H, 31P and 13C spectroscopy of metabolites in vivo
NMR microscopy
- volume selective spectroscopy of small laboratory animals