Obesity, bariatric surgery and eating disorders

This multidisciplinary research team is involved in several clinical projects and National Institutes of Health-funded clinical trials that examine the influence of psychological functioning and neurobiology on eating disorders and obesity. Through these investigations, the goal is to improve long-term treatment outcomes.

Research is conducted at Mayo Clinic campuses in Rochester, Minn., and Jacksonville, Fla.


  • Bariatric surgery. This research focuses on the impact of behavioral interventions on bariatric surgery outcomes, including obesity treatment in primary care and the prevalence of manic symptoms and food addiction in bariatric surgery patients.
  • Pediatric studies. This area focuses on understanding adolescents' preferences for social support in developing a healthy lifestyle and the effects of training children and their parents in stress management and mindful-eating based on body mass index and cardiovascular risk markers.
  • Eating disorders. This research works with functional MRI to understand the neurobiological aspects of anorexia and bulimia. Additional studies examine the role of family in adolescent eating disorders and exploring whether athletes with eating disorders differ from nonathletes. The application of nonexercise activity thermogenesis to anorexia represents a novel method to understand and monitor weight regulation.



Investigator & Role Grant Title Funding Source Duration
Adrian Vella, M.D. principal investigator Adjustable Gastric Banding and Its Effects on Postprandial Glucose Metabolism Independent of Weight Loss National Institute of Diabetes and Digestive and Kidney Diseases 07/2010-06/2014
Michael Camilleri, M.D., principal investigator Pharmacogenomics of Gastric Function and Weight in Obesity National Institute of Diabetes and Digestive and Kidney Diseases 09/2004-09/2015
Florencia G. Que, M.D., principal investigator ReCharge: A Prospective, Randomized, Blinded, Parallel-Group, Multicenter Trial to Evaluate the Safety and Efficacy of the Maestro RC2 System in Treating Obesity EnteroMedics, Inc. 05/2011-10/2016
Leslie A. Sim, Ph.D., L.P., principal investigator An Evaluation of an Online, Family-Based Indicated Prevention Program for Adolescent Eating Disorders Mayo Clinic Department of Psychiatry and Psychology Small Grants Program 05/2012-05/2014