Richard J. Bram, M.D.
"CAML in Normal and Oncogenic Functions of the EGFR"
The goals of this project are to elucidate the mechanism of CAML action in EGFR-mediated proliferation and determine the participation of CAML in EGFR-induced oncogenesis.
"Role of TACI in B cell Function and Transformation"
The goals of the project are to determine the mechanism of action of the Tumor Necrosis Factor Receptor family member TACI in the activation and transformation of B cells.