The Department of Cancer Biology at Mayo Clinic in Florida has 10 principal investigators who work collaboratively to understand the biology of human cancer and translate that knowledge into better methods of cancer diagnosis, prevention and treatment.

The department is an integral part of Mayo Clinic Cancer Center, a single National Cancer Institute-designated comprehensive cancer center that spans Mayo Clinic's three campuses in Arizona, Florida and Minnesota.

Research in the department is focused on nearly all the major causes of cancer-related deaths in the U.S., including breast, lung, colon, brain, pancreatic, liver, thyroid, ovarian and kidney cancer.

While many types of cancer are investigated, work is connected by a common theme: the molecular mechanisms of carcinogenesis. Faculty members study all stages of tumor progression, including early tumorigenesis, malignant progression, invasion and metastasis. Particular strengths exist in studying tumor invasion and metastasis, a key event during tumor progression that accounts for more than 90 percent of cancer-related mortality.

Importantly, department faculty members work closely with clinical colleagues across all three Mayo Clinic campuses to translate their laboratory research findings into new clinical trials and novel therapeutic approaches available in the clinic.

Read more about the department.