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The Gene Expression Core (GEC), part of the Advanced Genomics Technology Center at Mayo Clinic, provides comprehensive services and technical support for the measurement of gene expression in clinical and nonclinical samples. The GEC serves customers from both inside and outside Mayo Clinic.
The GEC utilizes multiple state-of-the-art platforms — including microarray-based technologies from Affymetrix, Illumina and Agilent, and quantitative polymerase chain reaction (qPCR) instrumentation from Fluidigm and Applied Biosystems — for a variety of gene expression analyses.
Services are also available for sample preparation for whole-genome messenger RNA (mRNA) and microRNA (miRNA) profiling by next-generation sequencing. The GEC currently provides whole-transcriptome and miRNA expression analyses of RNA derived from fresh-frozen tissues; formalin-fixed, paraffin-embedded tissues; laser-capture microdissected cells; and cell lines.