Value Analysis Program

Photo of two Mayo Clinic staff members looking at an iPad

The Value Analysis Program conducts research to enhance health care delivery models within Mayo Clinic and influence health policy. Faculty members in the program have expertise in:

  • Health care delivery system and payment reform
  • Health economics and health services research
  • Quality and safety
  • Comparative effectiveness research

Areas of focus

Broadly, work in the program assesses:

  • How the organization of a health system impacts health care quality, utilization and outcomes
  • Diagnostic accuracy
  • Comparative effectiveness of different care delivery models

Results of projects carried out in the Value Analysis Program benefit patients in several ways, such as by ensuring high-quality, affordable and patient-centric health care as well as aligning optimal care delivery models with the tightening reimbursement environment. The program's work also helps Mayo Clinic maintain its leadership position in the national health policy discussion.


Evaluating new second-line agents for glycemic control in type 2 diabetes

People with diabetes have several choices for drugs that can help them achieve blood glucose control, but the drugs have varying costs and undefined comparative effectiveness. Using data from Optum Labs, researchers explored outcomes and costs associated with four commonly prescribed treatment regimens.

Findings showed that the least expensive, older drugs work best and that the regimen with sulfonylurea has the lowest cost per quality-adjusted life year and longest time to insulin dependence. Work is underway to reassess clinical guidelines and pharmacy formulary processes to ensure these findings reach clinicians and patients. Read the study abstract.

Increasing care value and predictability in Mayo's adult cardiac surgery practice

Physicians, surgeons and researchers evaluated a new care model for how adult cardiac surgery patients are managed at Mayo Clinic, asking whether some portion of that population was similar enough that they could be managed in a more uniform, structured way rather than relying on physicians to individually determine each patient's course of care.

They determined that such a uniform approach was appropriate for 67 percent of cardiac surgery patients and, using industrial engineering principles and health information technology tools, crafted and implemented a new model for this segment of patients.

Results showed that the new model reduced hospital length of stay, costs and amount of resources used while also decreasing variation and improving outcomes. Read the study abstract.

Enhancing recovery in gynecologic surgery

In this study, the goal was to investigate the effects of enhanced recovery in people undergoing gynecologic surgery. Researchers compared a group of 241 patients who were managed with an enhanced recovery protocol after surgery with a control group of 235 past patients who received standard recovery care.

Enhanced recovery resulted in a four-day reduction in hospital length of stay, with stable readmissions rates and a 30-day cost savings of more than $7,600 per patient. Patient-controlled anesthesia use decreased from 98.7 percent in the control group to just 33.3 percent in the enhanced recovery group, and overall opioid use decreased by 80 percent in the first 48 hours after surgery with no changes in pain scores. Read the study abstract.


James M. Naessens, Sc.D.

Jayant A. Talwalkar, M.D., M.P.H.

Diane K. Olson