Pilot and Feasibility Grants

The goal of the Pilot and Feasibility Program is to enhance metabolomics research crucial to translational projects by providing investigators who are new to the metabolomics field the opportunity to explore the use of metabolomics in their research and support high-risk and high-impact research.

The Mayo Clinic Metabolomics Resource Core Pilot and Feasibility Program aims to form new multidisciplinary collaborations that will enhance the integration of the techniques offered at Mayo Clinic and benefit multiple investigators.

Potential applicants are encouraged to link basic, translational and clinical research. Extending the collaborative nature of research projects with funds from other mechanisms is encouraged.

The Mayo Clinic Metabolomics Research Core provides extensive services for metabolomics research with specific expertise in mass spectrometry and NMR spectroscopy utilizing stable isotope tracers to examine metabolic flux. Our facility specializes in measurement of targeted metabolites such as: amino acids and their metabolites; fatty acids and their metabolites; ceramides; citric acid cycle substrates; and phosphometabolites.


Mayo Clinic is one of six federally funded Regional Comprehensive Metabolomics Resource Cores (RCMRCs) to support medical research using metabolomics — the study of how molecules are metabolized at the cellular level. The purpose of the RCMRC program is to facilitate institutional development of pioneering research, metabolomics training and outreach programs in this emerging area.

The supporting grant (U24DK100469) is coordinated by the National Institute of Diabetes and Digestive and Kidney Diseases, but originates from the NIH Director's Common Fund.

K. Sreekumaran Nair, M.D., Ph.D., Endocrinology, is principal investigator and director of the Mayo Clinic Metabolomics Core Facility.

Application information


NIH Public Access Policy requires that all publication that results from NIH funding be uploaded to PubMed Central. Review the process for uploading publications.

Awardees must cite the Mayo Clinic Metabolomics Resource Core grant as a funding source in any resulting publications. Use this language:

This publication was made possible by Mayo Clinic Metabolomics Resource Core through grant number U24DK100469 from the National Institute of Diabetes and Digestive and Kidney Diseases and originates from the National Institutes of Health Director's Common Fund.