Overview

Illustration of stomach and esophagus

The Esophageal Adenocarcinoma and Barrett's Esophagus (EABE) Registry Consortium is a multi-center, multi-disciplinary, Academia-NIH-Industry collaboration designed to facilitate discoveries that will translate into improved patient outcomes. Since September 2001, the Registry has been prospectively collecting information about quality of life, symptoms and risk factors, as well as tissue and blood samples from patients with long segment Barrett's esophagus, squamous cell cancer of the esophagus, and esophageal adenocarcinoma.

Adenocarcinoma of the esophagus, which usually arises in a Barrett's esophagus, has been increasing in incidence in the United States by four to ten percent per year in recent decades. The cause of the increase is unknown. Similarly, the role of genetic factors in Barrett's esophagus is not known.

The EABE Registry Consortium provides a unique resource to help clinicians and scientists address important questions with sufficient power to yield meaningful results. We believe that such an undertaking can only be successfully achieved with the collaboration and support of partners in industry and at the NIH.