Lymphomas and chronic lymphocytic leukemia (CLL)

Lymphomas and chronic lymphocytic leukemia (CLL) are forms of cancer that originate in the bone marrow or lymph nodes. Rates of these cancers increased rapidly over much of the 20th century. CLL is the most common leukemia in the U.S. While we have made progress in understanding what causes these cancers and how to treat them, our knowledge is incomplete and there is still much to learn about how to prevent, diagnose and treat these cancers.

One major goal of this research program is to learn more about the environmental, lifestyle, genetic and biologic factors that might be responsible for causing lymphomas and CLL. We study individuals who have been recently diagnosed with these cancer and those who have never been diagnosed (controls). By comparing those two groups of people, we hope to uncover clues about the risk factors that might cause these diseases so that we can better prevent them. The other major goal of this research program is to learn about lifestyle, genetic, tumor and treatment factors that are associated with better cancer outcomes and survivorship among lymphoma and CLL patients. By studying patient outcomes over the long-term, we hope to improve survival, overall health and quality of life.