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The Skeletal Development and Regeneration Research Laboratory is studying protein phosphatase Phlpp1 in cartilage development and osteoarthritis progression.
This project studies how Hdacs and associated epigenetic factors control bone development and disease, which can help guide use of Hdac inhibitors and other epigenetic drugs in cancer treatment.
The Skeletal Development and Regeneration Research Laboratory is studying canonical and noncanonical Wnt signaling in osteoblast and osteoclast functions.
Dr. Westendorf's team is studying chromosomal translocations and cancer to discover and understand novel genes and mutations that contribute to bone cancers, sarcomas and leukemia.
The Skeletal Development and Regeneration Research Laboratory collaborates with research experts in genetic disorders, osteoporosis, osteoclasts, orthopedics and bone formation.
Funding for Dr. Westendorf's skeletal development research comes from the National Institutes of Health and the National Institute of Arthritis and Musculoskeletal and Skin Disease.
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