The research team discusses new projects. Project discussions

The lab focuses on a variety of projects ranging from oncology to neuroscience and many more.

Projects

Dr. Pandey's Molecular Imaging and Radionuclide Therapy Lab concentrates on research and clinical translation in these major areas:

  • Radioisotope production. The lab uses cyclotron targetry to produce radiometals to radiolabel radiopharmaceuticals.
  • Radiochemistry and automation. The lab supports the development of radiochemistry instrumentation and methods to support novel development of radiopharmaceuticals.
  • Radiopharmaceuticals for Alzheimer's disease. The lab analyzes positron emission tomography (PET)-related radiopharmaceutical approaches to studying the changes in biochemical process with Alzheimer's disease and correlates these changes with known interactions with tau protein depositions.
  • Fatty acid metabolism in heart and metabolic disorders. The lab investigates the development and use of fluorine-18-labeled fatty acid analogs to study fatty acid oxidation in cardiovascular diseases and metabolic disorders such as diabetes.
  • Sodium iodide symporter imaging. The lab studies the development and use of fluorine-18-labeled tetrafluoroborate and tetrafluoroborate analogs as PET probes to evaluate thyroid cancer and gene reporter probe for therapeutic viruses carrying the sodium iodide symporter gene.
  • Brain biochemistry in psychiatric disorders. The lab examines the use of metabolic imaging of neurochemical systems to understand disease pathology and predict and monitor treatment response.
  • Imaging and theranostics in glioblastomas. The lab pairs biomarkers of tumor aggressiveness with relevant treatment paradigms to improve treatment planning and monitor tumor response.
  • Noninvasive cell, virus and extracellular vesicle tracking methods. The lab aims to develop new methods to label and image cells, such as stem cells, dendritic cells, viruses (AAV9, AAVBR1), extracellular vesicles and others, to noninvasively monitor cell transport and survival.
  • Radionuclide therapy in oncology. The lab aims to develop new compounds that allow noninvasive PET imaging and radionuclide therapy without changing molecular structure, including alpha, beta and auger emitting isotopes.

This image provides an overview of the lab:

Infographic that shows an overview of the Molecular Imaging and Radionuclide Therapy Lab.