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Dr. Kullo's lab uses family history, linkage and association studies, and sequencing to research the genetics of arterial plaques (atherosclerosis).
The Atherosclerosis and Lipid Genomics Lab collaborates on projects conducting genetic studies of cardiovascular diseases using the electronic health record (EHR).
Dr. Kullo's lab is addressing challenges in implementing genomic medicine using the EHR through eMERGE projects, the MI-Genes study and other projects.
The lab is studying the prevalence, awareness, control and outcomes of familial hypercholesterolemia using electronic health records and registries such as CASCADE.
The Atherosclerosis and Lipid Genomics Lab is studying associations between circulating biomarkers and cardiovascular disease, such as myocardial infarction, ischemic stroke and heart failure.
Dr. Kullo's research team is investigating factors that influence arterial function and the effect of arterial function on ventricular function, such as through the GENOA study.
Research projects include using informatics approaches to ascertain PAD from the electronic health record, conducting population-based epidemiologic studies, and developing an automated estimation of prognostic scores for PAD with linkage to clinical decision support.
The lab created and maintains a biorepository to assist in the discovery of new biomarkers for vascular diseases, including peripheral artery disease and aortic aneurysm.
Collaborators from Mayo Clinic and across the country work with Dr. Kullo's team in an effort to advance understanding about the genetics of atherosclerotic cardiovascular diseases and hereditary lipid disorders.
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