Psychiatry and Psychology Research

Below are current clinical trials.

102 studies in Psychiatry and Psychology Research
(all studies, either open or closed).

Filter this list of studies by location, status and more.

1. 16-week Comparative Effectiveness Trial of Lamotrigine vs. Fluoxetine for Bipolar Depression

   Rochester, Minn., Austin, Minn.

   The FLAME Study is a 16-week clinical trial to study treatment with lamotrigine or fluoxetine in bipolar I, II and bipolar schizoaffective depressed adults. The purpose of the trial is to have a better understanding of whether individuals with a particular gene type and other inherited biological markers will have a good response to fluoxetine or lamotrigine, or alternatively, would be more likely to have side effects to this medication.

2. A Study of Cognitive Behavioral Therapy, Self-Effectivenss, and Depression in People with Chronic Pain

   Rochester, Minn.

   The purpose of this study is to explore the role of Cognitive Behavioral Therapy (CBT), a treatment for depression, on self-effectiveness (feeling empowered to accomplish a given task) and depression in persons with chronic pain and depression. Past research has shown that persons with chronic pain show improvement in self-efficacy and depression scores when they are using CBT. The Pain rehabilitation Center (PRC) at Mayo Clinic is adding CBT focused groups to better understand the role of CBT on self-efficacy and depression in persons with chronic pain and depression.

3. The relationship between a clinical tool and youth sports participation.

   Scottsdale/Phoenix, Ariz., Rochester, Minn.

   This study aims to describe the oculometric features extracted during K-D testing using eye-tracking that are associated with concussions in a youth sports population.

4. A Study to Learn About Self-injury in Children with Severe Intellectual and Developmental Disabilities

   Rochester, Minn.

   The overall goal of this study is to help discover and better understand why some children with intellectual  and developmental disabilities self-injure.

5. A Study of Cognitive Behavioral Cancer Stress Management (CBCSM) and its Effects on Cancer Distress

   Rochester, Minn.

   The purpose of this study is to test the effectiveness of cancer stress management (CBCSM) as a clinical service at Mayo Clinic.

6. Common Mechanisms of Anti-Suicidal Drug Action

   Rochester, Minn.

   The purpose of this study is to characterize the effects of clozapine, lithium, and ketamine on mTOR signaling, glucose uptake, and overall cellular metabolic function in peripheral blood mononuclear cells (PBMCs) from suicidal psychiatric inpatients.

7. Impact of Massage Therapy and Music Therapy on the Quality of Life of Hospice Patients

   Rochester, Minn.

   This is a cohort study where subjects will receive either massage therapy or music therapy interventions to evaluate their impact on hospice patients.

8. A Study of a Therapeutic Video Game for Social Anxiety in Children

   Rochester, Minn.

   The purpose of this study is to learn if children with social anxiety disorder find a therapeutic video game fun and helpful.

9. Systemic Inflammation Related to Mood Disorders

   Rochester, Minn.

   The overall goal is to better understand the underlying pathophysiology of mood disorders and bipolar disorders in particular. We aim to investigate whether the subclinical atherosclerotic and inflammatory markers differ between patients with bipolar disorder, major depressive disorder, and psychiatric non-mood disorders and healthy subjects.

10. A Study of the Use of Varenicline to Treat Smoking Addiction in Patients with Alcoholism

    Rochester, Minn.

    The purpose of this study is to see if varenicline will decrease alcohol consumption and increase alcohol abstinence rates when given to alcoholic patients for both alcohol and smoking cesation treatment.