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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

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  1. HPV Vaccine with or without Pembrolizumab for Human Papilloma Virus-related Cancer of the Head and Neck

    Rochester, MN

  2. Phase Ib/II of TG4001 and Avelumab in HPV16 Positive R/M Cancers

    Jacksonville, FL, Rochester, MN

  3. A Study to Validate HPV DNA Genotyping and Prognostic Genomic Biomarkers for Diagnosis

    Rochester, MN

  4. Female Patients and Female Partners of Patients With Confirmed HPV Associated Oropharyngeal Carcinoma (Pap-Op): Prospective Assessment of HPV Associated Anogenital Pathology

    Rochester, MN

  5. Human Papilloma Virus (HPV) Circulating Tumor DNA (ctDNA) in Cervical Cancer

    Rochester, MN


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