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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 14 for

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  1. A Study to Evaluate the Influence of Pulse Electromagnetic Field Therapy on Myocardial Ischemia

    Scottsdale/Phoenix, AZ, Rochester, MN

  2. A Study to Assess Hyperphosphorylated Tau PET Binding in Primary Progressive Aphasia

    Rochester, MN

  3. A Study to Evaluate Improving PET Image Quality and Quantification by Using Motion Correction, Parametric Imaging and MAP Reconstruction

    Rochester, MN

  4. Young-adult normal FDG-PET database

    Rochester, MN

  5. Clinical Evaluation of a Transmit/Receive Head Coil for PET/MR Brain Studies

    Rochester, MN

  6. 18F-DOPA PET in Sarcoma Patients

    Jacksonville, FL

  7. Alzheimer's Disease Neuroimaging Initiative 3 (ADNI3) Protocol

    Jacksonville, FL, Rochester, MN

  8. Ga-DOTATATE PET for Localization of Phosphaturic Mesenchymal Tumors in Patients with Tumor Induced Osteomalacia

    Rochester, MN

  9. A Study of Clinical Evaluation of a PET/MR System

    Rochester, MN

  10. 18F-fluciclovine PET/MRI Imaging for the Detection of Tumor Recurrence After Radiation Injury to the Brain

    Jacksonville, FL

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