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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 21-30 of 34 for Epilepsy

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  • Study status: Open/Status Unknown
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  1. Human Blood and Tissues Repository for Neuroscience Research

    Jacksonville, FL

  2. Functional Brain Mapping by Means of Communication Practices

    Rochester, MN

  3. A Study to Establish an Enterprise Neurosurgery Biobank

    Rochester, MN

  4. A Study to Identify Clinical Characteristics and Biomarkers of Disease Outcome, Progression, and Treatment Response in Participants with Treatment-resistant Focal Epilepsy

    Rochester, MN

  5. Multiscale EEG Dynamics

    Rochester, MN

  6. A Study to Evaluate Biomarker Target Stimulation

    Rochester, MN

  7. A Study to Assess Peripherally Circulating Plasma Proteins and Clinical Risks to Differentiate Epileptic Seizure from Psychogenic Nonepileptic Seizure

    Rochester, MN

  8. A Study to Review Magnetic Resonance Imaging in Patients with Epilepsy

    Rochester, MN

  9. Is physical exercise associated with significant changes in the frequency or burden of spikes on EEG in children with epilepsy?

    Rochester, MN

  10. A Study of Multicenter Outcomes in Pediatric Status Epilepticus

    Rochester, MN

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