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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 31-40 of 1714

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  • Locations: Jacksonville, FL
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  1. A Study to Evaluate fMRI of Active Deep Brain Stimulation in Epilepsy

    Jacksonville, FL

  2. A Study of Epacadostat in Combination With Pembrolizumab and Chemotherapy in Subjects With Advanced or Metastatic Solid Tumors (ECHO-207/KEYNOTE-723)

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  3. A Study to Evaluate the Safety and Effectiveness of Anti-CD38 CAR-T in Relapsed or Refractory Multiple Myeloma Patients

    Jacksonville, FL, Rochester, MN

  4. Study to Evaluate Eradicating Barrett's Esophagus Using Radiofrequency Ablation or a Novel Hybrid Argon Plasma Coagulation Technique

    Scottsdale/Phoenix, AZ, Jacksonville, FL

  5. Dose Escalation Study of I-131-CLR1404 in Patients With Relapsed or Refractory Multiple Myeloma

    Jacksonville, FL

  6. Addition of Daratumumab to Combination of Bortezomib and Dexamethasone in Participants with Relapsed or Refractory Multiple Myeloma

    Jacksonville, FL

  7. Sorafenib Tosylate in Treating Patients With Desmoid Tumors or Aggressive Fibromatosis

    Jacksonville, FL, Rochester, MN

  8. Valchlor in the Treatment of Lichen Planopilaris

    Jacksonville, FL

  9. Cediranib Maleate and Selumetinib in Treating Patients With Solid Malignancies

    Jacksonville, FL, Rochester, MN

  10. A Study to Evaluate TG4050 in Ovarian Carcinoma

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

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