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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 37 for prostate cancer

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  • Study status: Open/Status Unknown
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  1. Pivotal Study of the NanoKnife System for the Ablation of Prostate Tissue

    Rochester, MN

  2. Study of Cabozantinib Combined With Atezolizumab Vs. Second Novel Hormonal Therapy in Subjects with Metastatic Castration-Resistant Prostate Cancer

    Rochester, MN

  3. Testing the Effects of Oxybutynin for the Treatment of Hot Flashes in Men Receiving Hormone Therapy for Prostate Cancer

    Albert Lea, MN, Eau Claire, WI, Rochester, MN

  4. Two Studies for Patients With High Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a High Gene Risk Score

    Albert Lea, MN

  5. Vitamin D and Prostate Cancer Among African Americans

    Jacksonville, FL

  6. Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GS-5829 as a Single Agent and In Combination With Enzalutamide in Participants With Metastatic Castrate-Resistant Prostate Cancer

    Scottsdale/Phoenix, AZ

  7. MR-Guided Cryoablation of Prostate Bed Recurrences

    Rochester, MN

  8. Focal Laser Ablation of Prostate Cancer Tumors

    Rochester, MN

  9. A Study to Assess Multiparametric MRI in Evaluating Cancer Stage and Helping Treatment Planning in Patients with Prostate Cancer

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  10. A Study of AMG 757 in Participants With Neuroendocrine Prostate Cancer

    Scottsdale/Phoenix, AZ

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