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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 1-10 of 13 for Sleep Medicine

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  • Study status: Open/Status Unknown
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  1. Treating Sleep Apnea Induced Hypoxemia With Oxygen in Acute Stroke Patients

    Rochester, MN

  2. A Study to Compare the Feasibility and Effectiveness of SHUT-I vs. Standard Care for Insomnia Management in Fibromyalgia Patients

    Rochester, MN

  3. Study to Assess the Safety and Effectiveness of Oral BTD-001 in Adults with Idiopathic Hypersomnia

    Scottsdale/Phoenix, AZ, Rochester, MN

  4. Sleep for Stroke Management and Recovery Trial

    Jacksonville, FL

  5. Glasses for Adolescent Delayed Sleep-Wake Phase Disorder (GLAD)

    Rochester, MN

  6. A Study to Evaluate the Use of a Smartphone App for Stroke Patients with Obstructive Sleep Apnea

    Rochester, MN

  7. A Study to Evaluate Sleep for Stroke Management and Recovery

    Rochester, MN

  8. A Study to Compare Transverse Diagnostic Methods in Pediatric Patients After Polysomnogram for Diagnosis of Obstructive Sleep Apnea

    Rochester, MN

  9. A Study to Evaluate Treatment of Delayed Sleep-Wake Phase Syndrome with Melatonin in Patients with Comorbid Alcohol Use Disorders

    Rochester, MN

  10. A Prospective Registry for Patients with REM Sleep Behavior Disorder and Polysomnographic REM Sleep without Atonia and Controls

    Rochester, MN

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