Inclusion Criteria:

• Adult lung transplant recipient during index admission.

• Medically cleared for PT/OT activity by the primary team.

• Demonstrates functional limitation appropriate for inpatient rehabilitation intervention.

• Able to participate in therapist-directed strengthening at the lowest clinically appropriate intensity.

• Agreeable to participate in strengthening intervention and research procedures, as required by the final regulatory pathway.

• Has baseline functional status measurable using AM-PAC and/or other prespecified PT/OT outcomes.

Exclusion Criteria:

• Hemodynamic or respiratory instability precluding therapy participation.

• Contraindication to resistance training per PT/OT, surgical, or medical precautions.

• Conditions when participation is not clinically appropriate, such as ECMO, intubation, open chest, unstable vasoactive medication requirements, lower-extremity injury or wound with weight-bearing restriction, severe delirium preventing participation, or refusal of research consent.

• Major neurologic event preventing meaningful participation in the intervention or outcome assessment.

• Immediate planned transfer to inpatient rehabilitation or discharge within 24 hours when insufficient time remains for baseline assessment and intervention exposure.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 09/01/2026. Questions regarding updates should be directed to the study team contact.