A Study Of Thromboelastograph Maximum Lysis And Allergic Reaction

Overview

About this study

A study to assess the correlation between thromboelastography-derived Maximum Lysis and allergic reaction severity across WAO grades

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Adults ≥18 years of age

  • Presentation to the ED with suspected allergic reaction, anaphylaxis, or angioedema based on chief concern

  • Ability to obtain thromboelastography during the acute presentation

Exclusion Criteria:

  • Known inherited coagulation or fibrinolytic disorders

  • Active major bleeding at presentation

  • Receipt of thrombolytic therapy

  • Inability to obtain thromboelastography promptly

  • Patients receiving therapeutic anticoagulation may be excluded from primary analyses or included in sensitivity analyses

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 06/01/2026. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Ronna Campbell, M.D., Ph.D.

Contact us for the latest status

More information

Publications

Publications are currently not available

Additional contact information

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Phone: 800-664-4542 (toll-free)

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