A Study Of Ultrasound Assessment Of Diaphragmatic Function Following Liposomal Bupivacaine Administration For Interscalene Nerve Blocks
Overview
Tab Title Description
Study type
ObservationalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Rochester, Minnesota: 26-000628
About this study
The purpose of this study is to determine if measuring diaphragm thickness via ultrasonography will show a decrease in muscle thickness on the ipsilateral side that a liposomal bupivacaine block was placed.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria:
Exclusion Criteria:
Patient refusal and contraindications of interscalene blockade due to patient factors such as: significant pulmonary insufficiency, pre-existing hemidiaphragmatic paralysis, brachial plexus or degenerative neuropathy, allergy to proposed local anesthetic medication, severe cervical spine disease, BMI >40 kg/m2, neck circumference >50cm, pre-existing thoracic/diaphragmatic operations, and failed preoperative interscalene blockade. Patient is unable to provide informed consent. Patient is pregnant. Patient pregnancy status will be obtained through standard of care at Mayo Clinic per Pre-Procedure Pregnancy Reasonably Excluded Guide (PREG) protocol
Note: Other protocol defined Inclusion/Exclusion Criteria may apply.
Eligibility last updated 03/25/2026. Questions regarding updates should be directed to the study team contact.
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Rochester, Minn.
Mayo Clinic principal investigator Carlos Mantilla, M.D., Ph.D. |
Contact us for the latest status |
|
More information
Publications
Publications are currently not available