A Study Of Glucagon-Like Peptide-1 Receptor Agonists In Postoperative Delirium
Overview
Tab Title Description
Study type
ObservationalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Rochester, Minnesota: 26-005432
About this study
The purpose of this study is to evaluate the impact that GLP-1 RAs have on the incidence and phenotype of postoperative delirium.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria:
60 years of age or older with diagnosis of T2DM
Planned to undergo non-cardiac, non-intracranial surgery
Estimated length of stay > 24 hours in the hospital
Exclusion Criteria :
Patient declines participation in the study
Patient lacks capacity to consent
Unable to communicate or participate in delirium assessments due to language barriers or sensory deficits (delirium assessments are not validated in languages other than English or with use of interpreter)
Incarcerated
Baseline encephalopathy or prior diagnosis of major neurocognitive disorder, including moderate or severe dementia
History of delirium
Acute neurologic injury within the preceding 6 months
Note: Other protocol defined Inclusion/Exclusion Criteria may apply.
Eligibility last updated 05/11/2026. Questions regarding updates should be directed to the study team contact.
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Rochester, Minn.
Mayo Clinic principal investigator Lindsay Guevara, M.D. |
Contact us for the latest status |
|
More information
Publications
Publications are currently not available