Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria:
1. Males and females aged 10-65 years.
2. MRI or arthroscopic images confirming the suitability for meniscus transplantation. Focal chondral defects that are suitable for resurfacing or small enough to be ignored will be included provided there is a general preservation of cartilage in the joint.
3. Patients undergoing an isolated primary/revision MAT procedure, or concomitant MAT with other knee procedures such as ligament reconstruction, realignment osteotomy, or cartilage resurfacing.
4. Medically suitable for meniscus transplantation.
5. Appropriate understanding of the language of the surgical center in terms of communication and reading.
6. Ability of the Patient or parent/guardian to provide informed consent.
Exclusion Criteria:
1. Patient aged less than 10 years and more than 65.
2. Presence of diffuse full thickness cartilage loss (widespread ICRS Grade III-IV chondral damage) and/or architectural remodeling of bone (i.e. flattening of condyle) in the knee of interest.
3. Significant medical comorbidities that limit patients from undergoing surgery.
4. Presence of confounding neuromuscular, genetic/congenital, or post-traumatic conditions.
5. Inability to comply with rehabilitation programs.