A Study Of Neurobehavioral Dysregulation Questionnaire (NBD‑Q) In DIAGNOSE CTE‑II
Overview
Tab Title Description
Study type
ObservationalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Scottsdale/Phoenix, Arizona: 26-002873
About this study
The purpose of this study is to evaluate the psychometric properties of the newly developed Neurobehavioral Dysregulation Questionnaire (NBD‑Q) in the DIAGNOSE CTE‑II cohort at Mayo Clinic Arizona to inform its inclusion as a study measure for neurobehavioral dysregulation in TES/CTE research.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria:
Currently enrolled in DIAGNOSE CTE‑II and scheduled for a research visit at Mayo Clinic Arizona.
Able to read and complete questionnaires in English.
Able and willing to provide informed consent for this pilot or to have consent via a legally authorized representative (LAR) with participant assent.
Willing and able to complete NBD‑Q at two timepoints approximately 2–4 weeks apart.
Exclusion Criteria:
Acute psychiatric or medical instability on the day of the Mayo visit such that, in the opinion of the PI or delegate, questionnaire completion would be unsafe or invalid.
Inability to read or understand English sufficiently to complete the NBD‑Q.
Severe cognitive, sensory, or motor limitations preventing meaningful self‑report completion, even with assistance.
Any condition that, in the judgment of the investigator, makes participation in this pilot infeasible.
Note: Other protocol defined Inclusion/Exclusion Criteria may apply.
Eligibility last updated 03/23/2026. Questions regarding updates should be directed to the study team contact.
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Scottsdale/Phoenix, Ariz.
Mayo Clinic principal investigator Jennifer Wethe, Ph.D. |
Contact us for the latest status |
|
More information
Publications
Publications are currently not available