A Study Of Autologous Platelet-Rich Plasma (PRP) And Protein Concentrate For Hip Osteoarthritis

Overview

About this study

The purpose of this study is to evaluate patient reported pain scores and validated functional scores after platelet-rich plasma and protein serum concentrate injection.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • All patients aged 18 and above with a diagnosis of hip osteoarthritis (Kellgren-Lawrence Score of 1-3) who are clinically identified by their physician as PRP injection candidates will be eligible. Informed consent must be obtained prior to their PRP injection appointment.

Exclusion Criteria: 

  • Patients under the age of 18 will not be considered for recruitment.

  • Subjects with an inability or unwillingness to give written informed consent

  • Subjects with documented hip dysplasia on radiographs or magnetic resonance imaging

  • Subjects with baseline platelet level of less than 150,000 per microliter

  • Subjects with previous surgery of the reference joint (osteotomy around the hip, open or arthroscopic osteochondroplasty for femoroacetabular impingement)

  • Subjects with concurrent rheumatologic disease

  • Subjects with systemic disorders such as diabetes, bleeding disorders, cardiovascular disease, infections, and immune system disorders, coagulation disorders

  • Subjects with an intra-articular hip joint corticosteroid injection within the previous 3 months

  • Subjects with any intra-articular biologics injection within the previous 6 months

 

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 02/09/2026. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Steven Poon, M.D.

Contact us for the latest status

More information

Publications

Publications are currently not available

Additional contact information

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