Radiographic And Clinical Evaluation Of Surgical Treatment For Cervical Deformity: A Multi-Center Study 2.0

Overview

About this study

Multi-center, prospective, non-randomized study to evaluate outcomes of surgically treated patients with adult cervical spinal deformity.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • ≥18 years old at time of treatment

  • Diagnosis of cervical deformity- must meet one or more of the following criteria:

    • C2-C7 sagittal kyphosis (Cobb > 15 degrees)

    • T1S-CL > 35o

    • Segmental cervical kyphosis > 10 degrees between any 2 vertebra between C2-T1 or > 15 degrees across any 3 vertebra between C2-T1

    • Cervical scoliosis > 10 degrees (Cobb angle must include end vertebra within the cervical spine)

    • C2-C7 SVA > 4cm

    • McGregor's slope > 20 degrees or CBVA > 25 degrees

  • Plan for surgical correction of cervical deformity in the next 6 months

  • Willing to provide consent and complete study forms at baseline and follow-up intervals

Exclusion Criteria:

  • Active spine tumor or infection

  • Deformity due to acute trauma

  • Unwilling to provide consent or to complete study forms

  • Prisoner

  • Pregnant or immediate plans to get pregnant

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 02/02/2026. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Anthony Mikula, M.D.

Contact us for the latest status

Contact information:

Justice Story

5074225528

story.justice@mayo.edu

More information

Publications

Publications are currently not available