A Study Of GLP-1 Or GLP-1 RA/GIP On Menopausal Experience And Female Sexual Function

Overview

About this study

The purpose of this study is to evaluate the influence of GLP-1 RA or GLP-1 RA/GIP-mediated weight loss on female sexual dysfunction and associated distress at all ages.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Women aged 18 years and above

  • Diagnosed with premenopause, perimenopause, menopause, or postmenopausal.

  • Patients consulting Mayo Clinic’s Women’s Health Internal Medicine (WHIM) for weight management and women who presented to Mayo Clinic Arizona and Endocrinology weight management clinics wo are initiated on these medications

  • Prescribed GLP-1 or GLP-1 RA/GIP agonists for weight management as part of their treatment plan.

  • Willing and able to provide informed consent

Exclusion Criteria:

  • Concurrently starting medications specifically influencing female sexual function, including hormonal therapies, SSRI medications

  • Concurrently started medications specifically addressing menopausal symptoms, such as hormone therapies, SSRI medications, Gabapentin or Oxybutynin.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 12/31/2025. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Suneela Vegunta, M.D.

Contact us for the latest status

Contact information:

Mohammed Dheyaa Marsool

4805745709

marsool.mohammeddheyaa@mayo.edu

Rochester, Minn.

Mayo Clinic principal investigator

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More information

Publications

Publications are currently not available