Inclusion Criteria:

• Patients must be at least 18 years old.

• Patients must have planned surgery for resection of a newly diagnosed or recurrent glioma.

• Patients with tumors located in the brain cortex or superficial white matter in which introduction of the ultrasound probe is straightforward and does not pose a risk for intraoperative complications.

• Patients must have a Karnofsky performance status ≥60%

• Patient or LAR willing to provide written informed consent.

Exclusion Criteria: 

• Patients with deep-seated brain tumors in which introduction of the ultrasound probe poses an increased risk.

• Patients with a history of any brain infections.

• Patients with implanted devices

• Patients with any other neurological/neurosurgical disease that could affect tissue stiffness.

• Patients with any other structural brain defect that could affect tissue stiffness.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 06/14/2024. Questions regarding updates should be directed to the study team contact.