A Study Of Obesity Phenotypes To Improve Outcomes After Transcatheter Aortic, Mitral, And Tricuspid Valve Interventions
Overview
Tab Title Description
Study type
ObservationalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Rochester, Minnesota: 25-006013
About this study
The purpose of this study is to To evaluate clinical outcomes mortality, hospital readmissions, procedural complications) among obese patients undergoing Transcatheter Aortic Valve Replacement (TAVR) stratified by BMI.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria:
Age ≥18 years.
(Retrospective) Underwent TAVR, mitral or tricuspid TEER, TMVR or TTVR between 2015–2024.
(Prospective) Scheduled for TAVR, mitral or tricuspid TEER, TMVR or TTVR after June 30th
Documented obesity defined as either:
BMI ≥30, or
BMI ≥27 with one or more weight-related comorbidities (e.g., hypertension, dyslipidemia, obstructive sleep apnea, or cardiovascular disease)
within 6 months of the procedure.
Able to consent and complete pre-procedural visit.
Exclusion Criteria:
Note: Other protocol defined Inclusion/Exclusion Criteria may apply.
Eligibility last updated 5/29/2025. Questions regarding updates should be directed to the study team contact.
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
More information
Publications
Publications are currently not available