A Study Of Vaginal Cuff Closure Direction On Surgical Outcomes And Patient-reported Pelvic Dysfunction

Overview

About this study

The purpose of this study is to compare the effect of vaginal cuff closure direction on all postoperative vaginal cuff complications.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Patients undergoing laparoscopic or robotic total hysterectomy

  • Benign and malignant; fewer than 25% of patients will have malignancy

  • Ages 18-85 years old

  • American Society of Anesthesiologists (ASA) class I, II, or III

Exclusion Criteria:

  • Vaginal hysterectomy

  • Vaginal approach for cuff closure

  • Conversion to laparotomy

  • Concurrent vaginectomy, radical hysterectomy, or bowel resection

  • Concurrent prolapse and incontinence procedures

  • History of pelvic radiation or brachytherapy

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 6/12/2025. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Jamal Mourad

Open for enrollment

Contact information:

Thierry Ilela

(480) 574-3320

ilela.thierry@mayo.edu

More information

Publications

Publications are currently not available