A Study Of Milk Consumption In Metabolic Syndrome

Overview

About this study

The primary purpose of this study is to determine the impact of whole-fat milk consumption on cardiovascular and metabolic risk factors and peripheral vascular function in adults with metabolic syndrome.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Metabolic syndrome as defined as the presence of 3 of the following risk factors:

    • Fasting plasma glucose ≥100 mg/dL (or medical therapy for elevated glucose)

    • HDL-C <40 mg/dL in men or <50 mg/dL in women (or medical therapy for reduced HDL-C)

    • Triglycerides ≥150 mg/dL (or medical therapy for elevated triglycerides)

    • Waist circumference >102 cm for men and >88 cm for women

    • Systolic blood pressure ≥130 mmHg or diastolic blood pressure ≥80 mmHg (or medical therapy for hypertension)

  • Age between 18 and 70 years of age

Exclusion Criteria:

  • Cardiovascular disease diagnosis

  • Type 1 or 2 diabetes diagnosis

  • Milk allergy or lactose intolerance

  • Self-reported high baseline dairy intake (>3 servings per day)

  • >3 hours of physical activity per week

  • Pregnant women

  • Inflammatory bowel disease

  • Chronic steroid use

  • GLP-1 agonist use

  • Patients on medications related to metabolic syndrome where dose adjustments are planned to be made during the study period.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 10/06/2025. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Joshua Smith

Contact us for the latest status

Contact information:

Eric Bruhn

(507) 422-0220

bruhn.eric@mayo.edu

More information

Publications

Publications are currently not available