CBT Based Pain Management Program for the Treatment of Aromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS) in Breast Cancer Survivors

Overview

About this study

We propose a novel intensive multidisciplinary intervention based on Cognitive Behavioral Therapy (CBT) Principles to treat AIMSS. CBT based approaches are effective in managing pain, but this approach has never been used to treat AIMSS. Our plan is to complete one treatment group a month with a census of 10 patients per group totaling 50 patients treated in approximately 5 months. We will run additional groups if needed to hit our target of 50 treated patients. Fifty additional patients will be randomized to the Control arm of the study (Treatment as usual). All patients will be assessed at baseline and 3 and 6-month intervals.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria: 

  • Female ≥ 18 years old
  • ECOG ≤ 2, stage 0-III HR+ breast cancer in need of strategies to reduce symptoms and improve quality of life.

Exclusion Criteria:

  • Less than 18 years of age. 

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 1/30/2025. Questions regarding updates should be directed to the study team contact.
 

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Jacksonville, Fla.

Mayo Clinic principal investigator

Barbara Bruce, Ph.D., L.P.

Open for enrollment

Contact information:

Alejandra Cuartas-Abril M.S.

(904) 956-8885

Cuartas-Abril.Alejandra@mayo.edu

More information

Publications

Publications are currently not available