Advancing Skin Cancer Prevention And Treatment Through DNA Repair Enzymes: A Clinical Approach In Solid Organ Transplant Recipients

Overview

About this study

The purpose of this study is to determine whether the application of topical DNA repair enzymes results in a statistically significant reduction in facial photodamage compared to sunscreen alone in solid organ transplant recipients (SOTRs).

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Adults > 21-year-old.

  • Solid organ transplant recipient for one year and beyond.

  • Medical history of actinic keratoses and non-melanoma skin cancer.

Exclusion Criteria: 

  • Pediatric patients.

  • A medical history of malignancy other than nonmelanoma skin cancer.

  • Cutaneous field of cancerization treatment in the previous 12 months.

  • Inability to comply with research procedures.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 1/27/2025. Questions regarding updates should be directed to the study team contact.
 

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Jacksonville, Fla.

Mayo Clinic principal investigator

Thais Pincelli, M.D.

Contact us for the latest status

Contact information:

Thais Pincelli M.D.

(904) 953-6402

Pincelli.Thais@mayo.edu

More information

Publications

Publications are currently not available