mHealth App for Caregiver Instructino for Chemotherapy-Induced Peripheral Neuropathy

Overview

About this study

The purpose of this study is to assess the impact of home-based utilization of the PNR program on cancer survivors with CIPN and caregivers applying the instruction, and to develop a mobile application that will deliver the instructional program.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Must have received platinum and/or taxane chemotherapy for adjuvant treatment of a solid tumor.
  • Screens positive for moderate to severe CIPN with a 4+ on a 0-10 scale, with 0 being no numbness/tingling or pain in hands or feet and 10 being most severe imaginable.
  • Last chemo dose must be 6+ months in the past (as noted in A.1, symptoms persist in 30% of recipients > 6 months, this assures those with established chronicity are included, reducing likelihood of spontaneous improvement). Also, no new chemotherapy should be anticipated during the study course.
  • Must have internet access.

Exclusion Criteria:  

  • Other potential cause of neuropathy (e.g., diabetes).
  • Ongoing treatment with a neuropathy-causing medication,.
  • History of oncology massage therapy for neuropathy in the last 3 months,
  • Unstable lymphedema—if the patient is considered at risk of lymphedema, they can participate because level 2 pressure is deemed safe; however, if patient has had lymphedema, their condition must be declared stable by a certified lymphedema therapist (if stable, level 2 pressure is safe for this study’s interventions).
  • Stage IV patients are excluded because many are on active medications that continue to cause or exacerbate neuropathy, and would confound results; active metastases introduce increased risks with massage; and general comfort massage for supportive care would be more indicated than targeting CIPN.,

Note: Other protocol defined Inclusion/Exclusion criteria may apply.

Eligibility last updated 12/11/23. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Jacksonville, Fla.

Mayo Clinic principal investigator

Cindy Tofthagen, Ph.D., R.N.

Open for enrollment

Contact information:

Ann Dunshee C.M.A.

(904) 953-5102

Dunshee.Ann@mayo.edu

More information

Publications

Publications are currently not available