Inclusion Criteria:

• aged 18 and older
• ability to provide informed consent

Exclusion Criteria:

• implanted active devices such as cardiac defibrillators/pacemakers, deep brain stimulators, vagus nerve stimulators, intrathecal pumps, cochlear implants
• devices, or residual parts thereof left in the body such as cardiac pacer wires, which provide life assist, bone growth or pain management
• structural support devices, screws, or wires in bone that are near the spinal cord or temperature sensitive organs
• reconstructive metallic implants near the orbits
• external devices, medicinal patches, piercings, jewelry, clothing or hair accessories (such as wigs, weaves and extensions) within to the radiofrequency coil that cannot be removed from the body
• pregnancy
• tattoos located within to the radiofrequency coil
• metallic fragment in the eye
• fever / elevated temperature
• suffer from claustrophobia
• for 2H deuterium-MRI exams, subjects who are in a current diabetic ketoacidosis or hyperosmolar hyperglycemic state will be excluded from participation in this study.
• For 1H hydrogen MRI in subjects receiving a gadolinium-based contrast agent, subjects with a known allergy to these agents will be excluded from participation in this study.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 2/14/2024. Questions regarding updates should be directed to the study team contact.