Helmsley 3.0 Abbreviated Magnetic Resonance Enterography (MRE)

Overview

About this study

The purpose of our study is to compare a novel abbreviated MRE protocol to conventional, standard of care MRE in children and adults with CD at three large medical centers, with CCHMC serving as the lead site.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Established Crohn’s disease diagnosis in patients 18 years of age and older
  • Undergoing clinical MRE examinations for any reason(s) below:
    • Staging / restaging / follow-up of intestinal inflammation E
    • Evaluation of known or suspected luminal narrowing / stricturing disease
    • Evaluation of known or suspected internal penetrating disease

Exclusion Criteria:

  • Undergoing initial imaging for suspected CD where the diagnosis of CD has yet to be definitively established
  • New CD diagnosis, undergoing baseline imaging
  • Isolated colonic disease
  • Known or suspected pregnancy
  • Contraindication to MRI (e.g., due to certain implanted medical devices)
  • Ileostomy or prior ileal resection
  • Less than 18 years of age
  • Unable or unwilling to follow imaging procedures
  • Non-English speaking

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 4/11/2024. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Jeff Fidler, M.D.

Open for enrollment

Contact information:

Kristin Fritz

(507) 293-0925

Yaggy.Kristin@mayo.edu

More information

Publications

Publications are currently not available