Nanopore Sequencing for Detecting Bacteria in Bile and Preventing Surgical Site Infections in Patients Undergoing Surgery for Benign or Malignant Pancreatic Tumors


About this study

The objectives of this study are to reduce the rate of bacterobilia driven surgical site infection (SSI) in patients undergoing pancreatic head resection by providing surgical team with NS data in the post-operative setting, and to reduce cost of care through reduction in SSI and improved antibiotic stewardship.




Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • ≥ 18 year old (yo) male (M) or female (F).
  • Undergoing pancreaticoduodenectomy or total pancreatectomy for any benign or malignant indication with informed consent.
  • Women who are pregnant.

Exclusion Criteria:

  • Patients who are institutionalized or incarcerated.
  • Patients without the cognitive capacity to consent.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Marina Walther-Antonio, Ph.D.

Closed for enrollment

Contact information:

Danielle Patnode M.P.H.

(507) 538-4110

More information


Publications are currently not available