A Study to Compare the Effectiveness of Adductor Canal Pain Catheters Following Total Knee Arthroplasty


About this study

This study aims to compare postoperative pain levels between three (3) treatment groups, using the Numerical Rating Scale (NRS).


Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Age ≥ 18 and ≤ 90 years.
  • Willing to participate in the study and competent to provide informed consent.
  • Willing to comply with protocol procedures.
  • Has an underlying diagnosis of osteoarthritis indicated for a total knee arthroplasty.

Exclusion Criteria:

  • The patient must not have taken a schedule II narcotic daily, for 7 consecutive days, during the 3 months leading up to the surgery.
  • The patient must not be allergic or intolerant to a medication used in the multimodal pain pathway.
  • Revision knee arthroplasty.
  • Uncontrolled diabetes with A1C > 8.0%.
  • Pregnant patients.

Eligibility last updated 6/2/22. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Jacksonville, Fla.

Mayo Clinic principal investigator

Benjamin Wilke, M.D.

Open for enrollment

Contact information:

Stephanie Giles

(904) 953-9406


More information


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