Myocardial Blood Volume Measurement by Real-Time Myocardial Perfusion Echocardiography Correlates to Myocardial Compressibility by Cardiac Magnetic Resonance Imaging in Healthy Subjects


About this study

The purpose of this study is to evaluate the standard Myocardial Blood Volume Measurement (MBV) by Real-Time Myocardial Perfusion Echocardiography (RTMPE) and compare this to the myocardial volume ratio by Cardiac Magnetic Resonance (CMR).

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Age ≥ 18 years.
  • Available for testing performed in Rochester, MN.
  • Willing to undergo both an echocardiogram with RTMPE and CMR.
  • Study subject providing consent.

Exclusion Criteria:

  • Adults < 18 years.
  • BMI <30 kg/m^2.
  • Hypertension.
  • Diabetes Mellitus.
  • Stroke.
  • Cardiomyopathy or structural heart disease.
  • Known coronary artery disease or history of myocardial infarction.
  • Contraindication to echo enhancement agent or gadolinium administration such as an allergy.
  • Renal GFR < 50 mL/mL.
  • Females who are pregnant.
  • Subject unwilling to consent.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Courtney Bennett, D.O.

Closed for enrollment

Contact information:

Steven Zincke

(507) 255-0607

More information


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