Study of Characteristics of Chronic Rhinosinusitis Sub-types


About this study

There are many subtypes of CRS. Different subtypes respond better to different types of treatments. The purpose of this study is to develop a standard way to classify the subtypes of CRS so that the patients can be treated with a more individualized approach.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Adult patients presenting with sinonasal complaints or diagnosis of  Chronic Rhinosinusitis (CRS) to the PI’s clinic.
  • Willing and able to provide a written, informed consent. 

Exclusion Criteria:

  • Unable to undergo nasal endoscopy or CT scan.
  • Pregnant women.
  • Patients on chronic oral steroid therapy.
  • Prisoners and institutionalized patients.
  • Patients at very high risk of bleeding due to elevated bleeding profile, being on multiple blood thinners or significant thrombocytopenia.
  • Patients with neutropenia or those deemed clinically to be significantly vulnerable to post-biopsy infection.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Devyani Lal, M.D.

Closed for enrollment

Contact information:

Devyani Lal M.D.

More information


Publications are currently not available